536 research outputs found
Operating experience with four 200 kW Mod-0A wind turbine generators
The windpowered generator, Mod-0A, and its advantages and disadvantages, particularly as it affects reliability, are discussed. The machine performance with regard to power availability and power output is discussed
The Fundamental Plane of Black Hole Accretion and its Use as a Black Hole-Mass Estimator
We present an analysis of the fundamental plane of black hole accretion, an
empirical correlation of the mass of a black hole (), its 5 GHz radio
continuum luminosity (), and its 2-10 keV X-ray power-law
continuum luminosity (). We compile a sample of black holes with primary,
direct black hole-mass measurements that also have sensitive,
high-spatial-resolution radio and X-ray data. Taking into account a number of
systematic sources of uncertainty and their correlations with the measurements,
we use Markov chain Monte Carlo methods to fit a mass-predictor function of the
form . Our best-fit results are , , and
with the natural logarithm of the Gaussian intrinsic scatter in the log-mass
direction . This result is a
significant improvement over our earlier mass scaling result because of the
increase in active galactic nuclei sample size (from 18 to 30), improvement in
our X-ray binary sample selection, better identification of Seyferts, and
improvements in our analysis that takes into account systematic uncertainties
and correlated uncertainties. Because of these significant improvements, we are
able to consider potential influences on our sample by including all sources
with compact radio and X-ray emission but ultimately conclude that the
fundamental plane can empirically describe all such sources. We end with advice
for how to use this as a tool for estimating black hole masses.Comment: ApJ Accepted. Online interactive version of Figure 7 available at
http://kayhan.astro.lsa.umich.edu/supplementary_material/fp
Shocked POststarbust Galaxy Survey I: Candidate Poststarbust Galaxies with Emission Line Ratios Consistent with Shocks
[Abridged] The Shocked POststarburst Galaxy Survey (SPOGS) aims to identify
transforming galaxies, in which the nebular lines are excited via shocks
instead of through star formation processes. Utilizing the OSSY measurements on
the Sloan Digital Sky Survey Data Release 7 catalog, we applied Balmer
absorption and shock boundary criteria to identify 1,067 SPOG candidates
(SPOGs*) within z=0.2. SPOGs* represent 0.2% of the OSSY sample galaxies that
exceed the continuum signal-to-noise cut (and 0.7% of the emission line galaxy
sample). SPOGs* colors suggest that they are in an earlier phase of transition
than OSSY galaxies that meet an E+A selection. SPOGs* have a 13% 1.4GHz
detection rate from the Faint Images of the Radio Sky at Twenty centimeters
survey, higher than most other subsamples, and comparable only to
low-ionization nuclear emission line region hosts, suggestive of the presence
of active galactic nuclei. SPOGs* also have stronger NaD absorption than
predicted from the stellar population, suggestive of cool gas being driven out
in galactic winds. It appears that SPOGs* represent an earlier phase in galaxy
transformation than traditionally selected poststarburst galaxies, and that a
large proportion of SPOGs* also have properties consistent with disruption of
their interstellar media, a key component to galaxy transformation. It is
likely that many of the known pathways to transformation undergo a SPOG phase.
Studying this sample of SPOGs* further, including their morphologies, active
galactic nuclei properties, and environments, has the potential for us to build
a more complete picture of the initial conditions that can lead to a galaxy
evolving.Comment: 19 pages, 19 figures, 3 tables, accepted to ApJ Supplements (Apr 13),
full sample is available on www.spogs.or
Design and Synthesis of Novel Quinone Inhibitors Targeted to the Redox Function of Apurinic/Apyrimidinic Endonuclease 1/Redox Enhancing Factor-1 (Ape1/Ref-1)
The multifunctional enzyme apurinic endonuclease 1/redox enhancing factor 1 (Ape1/ref-1) maintains genetic fidelity through the repair of apurinic sites and regulates transcription through redox-dependent activation of transcription factors. Ape1 can therefore serve as a therapeutic target in either a DNA repair or transcriptional context. Inhibitors of the redox function can be used as either therapeutics or novel tools for separating the two functions for in vitro study. Presently there exist only a few compounds that have been reported to inhibit Ape1 redox activity; here we describe a series of quinones that exhibit micromolar inhibition of the redox function of Ape1. Benzoquinone and naphthoquinone analogues of the Ape1-inhibitor E3330 were designed and synthesized to explore structural effects on redox function and inhibition of cell growth. Most of the naphthoquinones were low micromolar inhibitors of Ape1 redox activity, and the most potent analogues inhibited tumor cell growth with IC50 values in the 10−20 μM range
Boise State Open Educational Resources Staff Training
Join colleagues from the Library, eCampus, Learning Technology Solutions and the IDEA Shop for a morning of learning about OER. Goals include: 1) Participants will learn about OER and how we can help support faculty interested in adopting OER. 2) Participants will meet each other, learn what we do in our respective departments and how we can work together
Emergence of a STAT3 mutated NK clone in LGL leukemia
AbstractLarge granular lymphocyte (LGL) leukemia is a chronic clonal lymphoproliferative disorder. Here, a T-LGL leukemia patient developed NK-LGL leukemia with residual leukemic T-LGL. TCRVβ usage and CDR3 sequence drifts were observed with disease progression. A STAT3 S614R mutation was identified in NK but not T-cells in the mixed leukemic stage. Multiple, non-dominant T-cell clones with distinct STAT3 mutations were present throughout. Our results suggest that T and NK-LGL leukemia may share common pathogenesis mechanisms and that STAT3 mutation alone is insufficient to bring about clonal expansion. Mutational and immunological monitoring may provide diagnostic and therapeutic significance in LGL leukemia
GPUVerify: A Verifier for GPU Kernels
We present a technique for verifying race- and divergence-freedom of GPU kernels that are written in mainstream ker-nel programming languages such as OpenCL and CUDA. Our approach is founded on a novel formal operational se-mantics for GPU programming termed synchronous, delayed visibility (SDV) semantics. The SDV semantics provides a precise definition of barrier divergence in GPU kernels and allows kernel verification to be reduced to analysis of a sequential program, thereby completely avoiding the need to reason about thread interleavings, and allowing existing modular techniques for program verification to be leveraged. We describe an efficient encoding for data race detection and propose a method for automatically inferring loop invari-ants required for verification. We have implemented these techniques as a practical verification tool, GPUVerify, which can be applied directly to OpenCL and CUDA source code. We evaluate GPUVerify with respect to a set of 163 kernels drawn from public and commercial sources. Our evaluation demonstrates that GPUVerify is capable of efficient, auto-matic verification of a large number of real-world kernels
Welcome to the Twilight Zone: The Mid-Infrared Properties of Poststarburst Galaxies
We investigate the optical and Wide-field Survey Explorer (WISE) colors of
"E+A" identified post-starburst galaxies, including a deep analysis on 190
post-starbursts detected in the 2{\mu}m All Sky Survey Extended Source Catalog.
The post-starburst galaxies appear in both the optical green valley and the
WISE Infrared Transition Zone (IRTZ). Furthermore, we find that post-starbursts
occupy a distinct region [3.4]-[4.6] vs. [4.6]-[12] WISE colors, enabling the
identification of this class of transitioning galaxies through the use of
broad-band photometric criteria alone. We have investigated possible causes for
the WISE colors of post-starbursts by constructing a composite spectral energy
distribution (SED), finding that mid-infrared (4-12{\mu}m) properties of
post-starbursts are consistent with either 11.3{\mu}m polycyclic aromatic
hydrocarbon emission, or Thermally Pulsating Asymptotic Giant Branch (TP-AGB)
and post-AGB stars. The composite SED of extended post- starburst galaxies with
22{\mu}m emission detected with signal to noise >3 requires a hot dust
component to produce their observed rising mid-infrared SED between 12 and
22{\mu}m. The composite SED of WISE 22{\mu}m non-detections (S/N<3), created by
stacking 22{\mu}m images, is also flat, requiring a hot dust component. The
most likely source of this mid-infrared emission of these E+A galaxies is a
buried active galactic nucleus. The inferred upper limit to the Eddington
ratios of post-starbursts are 1e-2 to 1e-4, with an average of 1e-3. This
suggests that AGNs are not radiatively dominant in these systems. This could
mean that including selections able to identify active galactic nuclei as part
of a search for transitioning and post-starburst galaxies would create a more
complete census of the transition pathways taken as a galaxy quenches its star
formation.Comment: 13 pages, 11 figures, accepted for publication in the Astrophysical
Journa
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